But the high-profile partnership between Oprah and WW is coming to an end after nearly a decade — after Oprah revealed her weight loss journey involved more than diet control.

Oprah: uses weight-loss medication

In December, Oprah told People that she has used an unspecified weight loss drug. “I realized I’d been blaming myself all these years for being overweight, and I have a predisposition that no amount of willpower is going to control,” she told the outlet. “Obesity is a disease. It’s not about willpower — it’s about the brain.”

She said that she “released her own shame” about weight-loss medication and her doctor wrote her a prescription.

“I now use it as I feel I need it, as a tool to manage not yo-yoing,” she told People. “The fact that there’s a medically approved prescription for managing weight and staying healthier, in my lifetime, feels like relief, like redemption, like a gift, and not something to hide behind and once again be ridiculed for. I’m absolutely done with the shaming from other people and particularly myself.”

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The revelation comes as prescription anti-obesity medications like Ozempic have been gaining popularity and widespread use.

Oprah’s admission was met with mixed reaction from fans: some praised her for her candidness about the topic, while others said she was a hypocrite after years of promoting diet programs. (Oprah told People that she still used the Weight Watchers point system in her daily weight regimen.)

Parting ways with Weight Watchers

Two months after this announcement, Oprah announced she was stepping away from Weight Watchers. In a company release, WW announced that Oprah would not stand for re-election to their Board of Directors, and would also be donating her shares to the National Museum of African American History and Culture.

According to the release, the Board of Directors of Weight Watchers is “supportive” of her decision to donate the shares, and that Oprah would continue to “advise and collaborate” with the company, and she would host events on weight health.

“Weight health is a critically important topic and one that needs to be addressed at a broader scale,” Oprah said in a statement. “I plan to participate in a number of public forums and events where I will be a vocal advocate in advancing this conversation.”